| 4T1 cells | in vitro | plasmid | EZT-4T10-1 | Overcoming resistance to αPD-1 of MMR-deficient tumors with high tumor-induced neutrophils levels by combination of αCTLA-4 and αPD1 blockers target | Journal for ImmunoTherapy of Cancer | 2022 |
| 4T1 cells | in vitro | plasmid | EZT-4T10-1 | A Cell Penetrating Peptide, MTS-AR8, for Transfection of 4T1 Murine Breast Cancer Cells | Drug Delivery Letters | 2017 |
293T cells
G355-5 cells | in vitro | plasmid | EZT-EVDY-1 | Potentially reduced fusogenicity of syncytin-2 in New World monkeys | FEBS Open Bio | 2023 |
| HT29 cells | in vitro | plasmid | EZT-HT29-1 | Folic acid modulates cancer-associated micro RNAs and inflammatory mediators in neoplastic and non-neoplastic colonic cells in a different way | Molecular Nutrition & Food Research | 2017 |
| Human bladder smooth muscle cells | in vitro | siRNA | EZT-PRSC-1 | Silencing of Rac1 and Arf6 reduces time-dependent and carbachol-induced contractions, proliferation, survival and growth in human bladder smooth muscle cells | World Journal of Urology | 2025 |
U87 cells
U251 cells
T98G cells | in vitro and in vivo | siRNA | EZT-EVDY-1 | Ataxin-2 as a candidate blood biomarker for estimating disease status in cases of suspected glioblastoma recurrence | Brain Tumor Pathology | 2025 |
| Rat sarcoma XC cells | in vitro | plasmid | EZT-VIVO-1 | Polyprenol-Based Lipofecting Agents for In Vivo Delivery of Therapeutic DNA to Treat Hypertensive Rats | Biochemical Genetics | 2021 |
| BmN cells | in vitro | plasmid | EZT-EVDY-1 | Production of scFv, Fab, and IgG of CR3022 Antibodies Against SARS-CoV-2 Using Silkworm-Baculovirus Expression System | Molecular Biotechnology | 2021 |
non-MDS cells
MDS cells | in vitro | plasmid | EZT-HDF0-1 | Multi-Omics Approach Reveals Genes and Pathways Affected in Miller-Dieker Syndrome | Molecular Neurobiology | 2025 |
HeLa cells
HEK293T cells
SH-SY5Y cells | in vitro | plasmid | EZT-EVDY-1 | A depression-associated protein FKBP5 functions in autophagy initiation through scaffolding the VPS34 complex | Molecular Neurobiology | 2025 |
| CT-26 cells | in vivo | plasmid | EZT-CT26-1 | Chemoprevention by Microencapsulated Lactiplantibacillus Plantarum LAB12 Against Orthotopic Colorectal Cancer Mice is Associated with Apoptosis and Anti-angiogenesis | Probiotics and Antimicrobial Proteins | 2024 |
| HeLaM cells | in vitro | plasmid | EZT-EVDY-1 | Development of nanobody-based POLArIS orientation probes enabled multi-color/multi-target orientation imaging in living cells | Biochemical and Biophysical Research Communications | 2021 |
| MC3T3-E1 cells | in vitro | plasmid | EZT-EVDY-1 | Visualization of osteocalcin and bone morphogenetic protein 2 (BMP2) secretion from osteoblastic cells by bioluminescence imaging | Biochemical and Biophysical Research Communications | 2022 |
| SNRPD3 cells | in vivo | plasmid | EZT-EVDY-1 | Cancer-associated SNRPD3 mutation confers resistance to hypoxia, which is attenuated by DRP1 inhibition | Biochemical and Biophysical Research Communications | 2024 |
| TIG-1 fibroblast cells | No public access | No public access | No public access | Type IV collagen expression is regulated by Notch3-mediated Notch signaling during angiogenesis | Biochemical and Biophysical Research Communications | 2025 |
| SKOV-3 cells | in vitro | siRNA | EZT-SKOV-1 | Revisiting the value of competition assays in folate receptor-mediated drug delivery | Biomaterials | 2017 |
MC3T3-E1 cells
ST2 cells | in vitro | plasmid | EZT-EVDY-1 | Osteoprotegerin secretion and its inhibition by RANKL in osteoblastic cells visualized using bioluminescence imaging | Bone | 2025 |
| BmN cells | in vitro and in vivo | plasmid | EZT-EVDY-1 | Tributyltin-binding protein type 1 (fish acid glycoprotein) is a potential gatekeeper of ethinylestradiol action in fish | Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology | 2023 |
| HEK293 cells | in vitro | plasmid | Not available | A conserved gating element in TRPV6 channels | Cell Calcium | 2017 |
| COS-7 cells | in vitro | plasmid | EZT-COS7-1 | IP3-dependent Ca2+ signals are tightly controlled by Cavβ3, but not by Cavβ1, 2 and 4 | Cell Calcium | 2022 |
| HEK 293T cells | in vitro | plasmid | EZT-HMEC-1 | XIST loss impairs mammary stem cell differentiation and increases tumorigenicity through Mediator hyperactivation | Cell | 2021 |
| U251 Tspan15 knockout cells | in vitro | plasmid | EZT-U251-1 | Structural basis for membrane-proximal proteolysis of substrates by ADAM10 | Cell | 2023 |
| Early passage diploid lung fibroblast cells | in vitro | plasmid | EZT-HLF0-1 | Mig-6 participates in the regulation of cell senescence and retinoblastoma protein phosphorylation | Cellular Signalling | 2014 |
| PCa cell line | in vitro | plasmid | EZT-DU14-1 | Dissection of Axial-Pore Loop Function during Unfolding and Translocation by a AAA+ Proteolytic Machine | Cell Reports | 2015 |
| MEF cells | in vitro | plasmid | EZT-MEFS-1 | The PERK Arm of the Unfolded Protein Response Regulates Mitochondrial Morphology during Acute Endoplasmic Reticulum Stress | Cell Reports | 2018 |
| MCF10A cells | in vitro | plasmid | EZT-EVDY-1 | Cell Cycle Checkpoints Cooperate to Suppress DNA- and RNA-Associated Molecular Pattern Recognition and Anti-Tumor Immune Responses | Cell Reports | 2020 |
| NP5 cells | in vitro | plasmid | EZT-EVDY-1 | p53-independent tumor suppression by cell-cycle arrest via CREB/ATF transcription factor OASIS | Cell Reports | 2023 |
| HEK293T cells | in vitro | plasmid | EZT-EVDY-1 | The Chlamydia effector Dre1 binds dynactin to reposition host organelles during infection | Cell Reports | 2025 |
| MEF cells | in vitro | plasmid | EZT-MEFS-1 | Pharmacologic activation of a compensatory integrated stress response kinase promotes mitochondrial remodeling in PERK-deficient cells | Cell Chemical Biology | 2023 |
| No access | No public access | No public access | No public access | A novel MRGPRX2-targeting antagonistic DNA aptamer inhibits histamine release and prevents mast cell-mediated anaphylaxis | European Journal of Pharmacology | 2020 |
| No access | No public access | No public access | No public access | Silkworm FoxL21 plays important roles as a regulator of ovarian development in both oogenesis and ovariole development | Insect Biochemistry and Molecular Biology | 2022 |
| BmO2 cells | in vitro | plasmid | EZT-EVDY-1 | The biological role of core 1β1-3galactosyltransferase (T-synthase) in mucin-type O-glycosylation in Silkworm, Bombyx mori | Insect Biochemistry and Molecular Biology | 2023 |
| HEK 293T cells | in vitro | plasmid | Not available | Schlafen 14 (SLFN14) is a novel antiviral factor involved in the control of viral replication | Immunobiology | 2017 |
| Cancer stem cell-like cells | in vitro | plasmid | EZT-MDAM-1 | Unveiling transcriptional mechanisms of B7-H3 in breast cancer stem cells through proteomic approaches | iScience | 2025 |
| No access | No public access | No public access | No public access | Sophoricoside, a genistein glycoside from Fructus Sophorae, promotes hair growth via activation of M4 muscarinic AChR in dermal papilla cells | Journal of Ethnopharmacology | 2024 |
Human Dermal Fibroblasts cells
HaCaT cells | in vitro | plasmid | EZT-HDF0-1 | STING Is Involved in Antiviral Immune Response against VZV Infection via the Induction of Type I and III IFN Pathways | Journal of Investigative Dermatology | 2017 |
| COS-7 cells | in vitro | plasmid | EZT-COS7-1 | The stoichiometry of the TMEM16A ion channel determined in intact plasma membranes of COS-7 cells using liquid-phase electron microscopy | Journal of Structural Biology | 2017 |
| NRK-49F cells | in vivo | siRNA | EZT-VIVO-1 | Inhibition of the H3K4 methyltransferase MLL1/WDR5 complex attenuates renal senescence in ischemia reperfusion mice by reduction of p16INK4a | Kidney International | 2019 |
| WPMY-1 cells | No public access | siRNA | No public access | Silencing of CDC42 inhibits contraction and growth-related functions in prostate stromal cells, which is mimicked by ML141 | Life Sciences | 2023 |
| HEK 293T cells | in vitro | plasmid | EZT-EVDY-1 | BLM helicase unwinds lagging strand substrates to assemble the ALT telomere damage response | Molecular Cell | 2024 |
| NER-proficient cells | in vitro and in vivo | plasmid | EZT-EVDY-1 | An assay to detect DNA-damaging agents that induce nucleotide excision-repairable DNA lesions in living human cells | Mutation Research/Genetic Toxicology and Environmental Mutagenesis | 2017 |
| 4T1 cells | in vitro | plasmid | EZT-4T10-1 | Effect of MisMatch repair deficiency on metastasis occurrence in a syngeneic mouse model | Neoplasia | 2025 |
| U251 cells | in vitro and in vivo | plasmid | EZT-U251-1 | Crystal structure of the Tspan15 LEL domain reveals a conserved ADAM10 binding site | Structure | 2022 |
| NIH-3T3 cells | in vitro | plasmid | EZT-NIH3-1 | Mammalian knock out cells reveal prominent roles for atlastin GTPases in ER network morphology | Experimental Cell Research | 2016 |
| Neuro-2a cells | in vivo | plasmid | EZT-EVDY-1 | Phospholipid phosphatase related 1 (PLPPR1) increases cell adhesion through modulation of Rac1 activity | Experimental Cell Research | 2020 |
| SCC cells | in vitro | plasmid | EZT-EVDY-1 | Rac1-dependent phagocytosis of apoptotic cells by oral squamous cell carcinoma cells: A possible driving force for tumor progression | Experimental Cell Research | 2020 |
| C2C12 cells | in vitro | plasmid | EZT-C2C1-1 | Back to basics: Optimization of DNA and RNA transfer in muscle cells using recent transfection reagents | Experimental Cell Research | 2022 |
| Cx45CT cells | in vitro | plasmid | EZT-MDCK-1 | Intramolecular signaling in a cardiac connexin: Role of cytoplasmic domain dimerization | Journal of Molecular and Cellular Cardiology | 2017 |
| HEK293T cells | in vitro | plasmid | EZT-EVDY-1 | The TRIM33 Bromodomain Recognizes Histone Lysine Lactylation | ACS Chemical Biology | 2024 |
| SK-OV-3 cells | in vivo | siRNA | EZT-SKOV-1 | siRNA-Mimetic Ratiometric pH (sMiRpH) Probes for Improving Cell Delivery and mRNA Knockdown | ACS Chemical Biology | 2025 |
| bEnd3.1 cells | in vitro | siRNA | EZT-BEND-1 | IFN-γ promotes transendothelial migration of CD4+ T cells across the blood–brain barrier | Immunology & Cell Biology | 2017 |
HEK293T cells
hTERT-RPE1 cells | in vitro | plasmid | EZT-EVDY-1 | FAM21 directs SNX27–retromer cargoes to the plasma membrane by preventing transport to the Golgi apparatus | Nature Communications | 2016 |
| Jurkat T-ALL cells | in vitro | plasmid | EZT-MOLT-1 | Small genomic insertions form enhancers that misregulate oncogenes | Nature Communications | 2017 |
IGROV-1 cells
SKOV3 cells | | sgRNA | EZT-IGRO-1 | Regulation of miR-200c/141 expression by intergenic DNA-looping and transcriptional read-through | Nature Communications | 2016 |
| T84 colon epithelial cells | in vivo | siRNA | EZT-T840-1 | NOX1-derived ROS drive the expression of Lipocalin-2 in colonic epithelial cells in inflammatory conditions | Mucosal Immunology | 2019 |
| 786-O kidney cancer cells | in vitro | plasmid | EZT-EVDY-1 | Mutation of the proline P81 into a serine modifies the tumour suppressor function of the von Hippel–Lindau gene in the ccRCC | British Journal of Cancer | 2022 |
| HGrC1 cells | in vitro | plasmid | EZT-EVDY-1 | Primate-specific POTE-actin gene could play a role in human folliculogenesis by controlling the proliferation of granulosa cells | Cell Death Discovery | 2021 |
U251MG cells
HT1080 cells
DU145 cells
A549 cells
U87MG cells | in vitro | plasmid | EZT-EVDY-1 | Impact of cell cycle on repair of ruptured nuclear envelope and sensitivity to nuclear envelope stress in glioblastoma | Cell Death Discovery | 2023 |
| U251T cells | in vitro | plasmid | EZT-U251-1 | Carmofur prevents cell cycle progression by reducing E2F8 transcription in temozolomide-resistant glioblastoma cells | Cell Death Discovery | 2023 |
GC-2spd(ts) cells
293T cells | in vitro | plasmid | EZT-EVDY-1 | GALNTL5, which is restricted to mouse spermatids, impairs endoplasmic reticulum (ER) function through direct interaction with ER chaperone proteins | Cell Death Discovery | 2024 |
| THP1 cells | in vitro | sgRNA | EZT-EVDY-1 | The lysosomal Ragulator complex plays an essential role in leukocyte trafficking by activating myosin II | Nature Communications | 2021 |
LOX-IMVI cells
SK-MEL-30 cells
D4M-3A cells
HEK293T cells | in vitro and in vivo | plasmid | EZT-LOXI-1 | Constitutive expression of the transcriptional co-activator IκBζ promotes melanoma growth and immunotherapy resistance | Nature Communications | 2025 |
| Lenti-X 293 T cells | in vitro | plasmid | EZT-EVDY-1 | Cancer stem cell-like cells | Nature Communications | 2025 |
| BxPC3 cells | in vitro | plasmid | EZT-BXPC-1 | Spatiotemporal H2O2 flashes coordinate actin cytoskeletal remodeling and regulate cell migration and wound healing | Nature Communications | 2025 |
| HEK 293T cells | in vitro | plasmid | EZT-EVDY-1 | ER proteins decipher the tubulin code to regulate organelle distribution | Nature | 2022 |
| Plat-E cells | in vitro | plasmid | EZT-EVDY-1 | LAG-3 inhibits the activation of CD4+ T cells that recognize stable pMHCII through its conformation-dependent recognition of pMHCII | Nature Immunology | 2018 |
Plat-E cells
293T cells | in vitro | plasmid | EZT-EVDY-1 | PD-1 agonism by anti-CD80 inhibits T cell activation and alleviates autoimmunity | Nature Immunology | 2022 |
| Mouse Neuroblastoma Neuro-2a cells | in vitro | plasmid | EZT-NEUR-1 | Phosphorylation of the Transient Receptor Potential Ankyrin 1 by Cyclin-dependent Kinase 5 affects Chemo-nociception | Scientific Reports | 2018 |
| NHBE cells | in vitro | plasmid | EZT-HBEC-1 | The DsbA-L gene is associated with respiratory function of the elderly via its adiponectin multimeric or antioxidant properties | Scientific Reports | 2020 |
| HEK 293T cells | in vitro | plasmid | EZT-EVDY-1 | A single TRPV1 amino acid controls species sensitivity to capsaicin | Scientific Reports | 2020 |
| Hepa1c1c7 cells | in vitro and in vivo | siRNA | EZT-EVDY-1 | NF-E2-related factor 1 suppresses the expression of a spermine oxidase and the production of highly reactive acrolein | Scientific Reports | 2025 |
| TIB-73 cells | in vitro and in vivo | siRNA | EZT-MEFS-1 | A beneficial adaptive role for CHOP in driving cell fate selection during ER stress | EMBO reports | 2024 |
| KD3 cells | in vitro | plasmid | EZT-HSKM-1 | HnRNP C, YB-1 and hnRNP L coordinately enhance skipping of human MUSK exon 10 to generate a Wnt-insensitive MuSK isoform | Scientific Reports | 2014 |
| RBL-2H3 cells | in vivo | plasmid | EZT-RBL2-1 | CRACM3 regulates the stability of non-excitable exocytotic vesicle fusion pores in a Ca2+-independent manner via molecular interaction with syntaxin4 | Scientific Report | 2016 |
| MCF10A cells | in vitro | plasmid | EZT-MDAM-1 | Differential profiles of HDAC1 substrates and associated proteins in breast cancer cells revealed by trapping | Molecular Omics | 2021 |
| HEK293 cells | in vitro | plasmid | EZT-EVDY-1 | Identification of novel binding sites for heparin in receptor protein-tyrosine phosphatase (RPTPσ): Implications for proteoglycan signaling | Journal of Biological Chemistry | 2018 |
| Raji cells | in vitro | plasmid | EZT-RAJI-1 | Differential interactions of missing in metastasis and insulin receptor tyrosine kinase substrate with RAB proteins in the endocytosis of CXCR4 | Journal of Biological Chemistry | 2019 |
| Plat-E cells | in vitro | plasmid | EZT-EVDY-1 | Atypical motifs in the cytoplasmic region of the inhibitory immune co-receptor LAG-3 inhibit T cell activation | Journal of Biological Chemistry | 2019 |
| WPMY-1 cells | in vitro | siRNA | EZT-PRSC-1 | A NAV2729-sensitive mechanism promotes adrenergic smooth muscle contraction and growth of stromal cells in the human prostate | Journal of Biological Chemistry | 2019 |
| ARPE-19 cells | in vitro | siRNA | EZT-EVDY-1 | Glutathione Trisulfide Prevents Lipopolysaccharide-induced Inflammatory Gene Expression in Retinal Pigment Epithelial Cells | Ocular Immunology and Inflammation | 2022 |
| Colorectal cancer cells | in vitro and in vivo | siRNA | EZT-CACO-1 | Control of Intestinal Stemness and Cell Lineage by Histone Variant H2A.Z Isoforms | Molecular and Cellular Biology | 2024 |
| MEF cells | in vitro | plasmid | EZT-EVDY-1 | Direct homophilic interaction of LAMP2A with the two-domain architecture revealed by site-directed photo-crosslinks and steric hindrances in mammalian cells | Autophagy | 2021 |
HEK293T cells
HeLa cells
hTERT-RPE1 cells | in vitro | plasmid | EZT-EVDY-1 | TRIM22 facilitates autophagosome-lysosome fusion by mediating the association of GABARAPs and PLEKHM1 | Autophagy | 2024 |
U251MG cells
U87MG cells | in vitro | plasmid | EZT-EVDY-1 | VPS4B orchestrates response to nuclear envelope stress by regulating ESCRT-III dynamics in glioblastoma | Nucleus | 2024 |
HeLa cells
HEK293T cells | in vitro | plasmid | EZT-EVDY-1 | TRIM22 functions as a scaffold protein for autophagy initiation | Animal Cells and Systems | 2025 |
HEK 293T cells
HeLA cells | in vitro | plasmid | EZT-EVDY-1 | MiT/TFE transcription factors are activated during mitophagy downstream of Parkin and Atg5 | Journal of Cell Biology | 2015 |
| NIH-3T3 ATL1/2/3 TKO cells | in vitro | plasmid | EZT-EVDY-1 | The hypervariable region of atlastin-1 is a site for intrinsic and extrinsic regulation | Journal of Cell Biology | 2021 |
| Hepa1-6 cells | in vitro | siRNA | EZT-HEPA-1 | NAT10 and DDX21 Proteins Interact with RNase H1 and Affect the Performance of Phosphorothioate Oligonucleotides | Nucleic Acid Therapeutics | 2022 |
| SNB-19 cells | in vitro | plasmid
siRNA | EZT-U251-1 | Tetraspanins 10 and 15 support Venezuelan equine encephalitis virus replication in astrocytoma cells | Molecular Biology of the Cell | 2025 |
| 10T1/2 cells | in vitro and in vivo | plasmid | EZT-EVDY-1 | Cocoa extract induces browning of white adipocytes and improves glucose intolerance in mice fed a high-fat diet | Bioscience, Biotechnology, and Biochemistry | 2024 |
| C2C12 cells | in vitro | plasmid | EZT-C2C1-1 | Identification of a muscle-specific isoform of VMA21 as a potent actor in X-linked myopathy with excessive autophagy pathogenesis | Human Molecular Genetics | 2023 |
NIH-3T3 cells
COS7 cells | | mRNA | EZT-EVDY-1 | Reep1 null mice reveal a converging role for hereditary spastic paraplegia proteins in lipid droplet regulation | Human Molecular Genetics | 2016 |
| HEK293 cells | in vitro | plasmid | EZT-EVDY-1 | Old but not obsolete: an enhanced high-speed immunoblot | The Journal of Biochemistry | 2020 |
| HeLa cells | in vivo | plasmid | EZT-EVDY-1 | Genetically encoded orientation probes for F-actin for fluorescence polarization microscopy | Microscopy | 2019 |
| 293T cells | in vitro | plasmid | EZT-EVDY-1 | Dynamic Evolution of Retroviral Envelope Genes in Egg-Laying Mammalian Genomes | Molecular Biology and Evolution | 2023 |
| A431 cells | in vitro and in vivo | plasmid | EZT-A431-1 | Cellular uptake mediated by epidermal growth factor receptor facilitates the intracellular activity of phosphorothioate-modified antisense oligonucleotides | Nucleic Acids Research | 2018 |
U2OS cells
HeLa cells
NIH3T3 cells | in situ | plasmid | EZT-EVDY-1 | Cytoplasmic DNA can be detected by RNA fluorescence in situ hybridization | Nucleic Acids Research | 2019 |
HEK293 cells
HeLa cells | in vitro | plasmid | EZT-EVDY-1 | Intracellular Demethylation of Methylmercury to Inorganic Mercury by Organomercurial Lyase (MerB) Strengthens Cytotoxicity | Toxicological Sciences | 2019 |
| 293T cells | in vitro | plasmid | EZT-EVDY-1 | The hidden diversity of ancient bornaviral sequences from X and P genes in vertebrate genomes | Virus Evolution | 2023 |
| Rat cells (multiple tissue samples) | in vivo | plasmid | EZT-VIVO-1 | Cationic Derivatives of Polyisoprenoids and Commercial Lipid-Based DNA Carriers for Transfection in vivo in Spontaneously Hypertensive Rats | The FASEB Journal | 2019 |
| WPMY-1 cells | in vivo and ex vivo | siRNA | EZT-PRSC-1 | Isoform-independent promotion of contractility and proliferation, and suppression of survival by with no lysine/K kinases in prostate stromal cells | The FASEB Journal | 2024 |
| Cultured stromal cells | in vitro | miRNA | EZT-PRSC-1 | PD29-11 miR-143-3p PROMOTES CONTRACTILITY AND GROWTH IN BENIGN PROSTATE STROMAL CELLS, WHICH IS REDUCED BY TRANSFECTION WITH A miR-143-p INHIBITOR | Journal of Urology | 2025 |
| HL-60 cells | in vitro | plasmid | EZT-HL60-1 | Endogenous Retroviral Elements Generate Pathologic Neutrophils and Elastase Rich Exosomes in Pulmonary Arterial Hypertension | bioRxiv | 2021 |
| HEK293T cells | in vitro | plasmid | EZT-EVDY-1 | Chlamydia trachomatis effector Dre1 interacts with dynactin to reposition host organelles during infection | bioRxiv | 2022 |
| Hs27 fibroblast cells | in vitro | plasmid | EZT-WI38-1 | Human XIRP1 is a macrophage podosome protein utilized by Listeria for actin-based motility | bioRxiv | 2022 |
| HDF cells | in vitro and in vivo | plasmid
microRNA
siRNA | EZT-HDF0-1 | Sprr1 and miR-130b contribute to the senescence-like phenotype in aging | bioRxiv | 2023 |
| Human hair follicle dermal papilla cells | in vivo and ex vivo | plasmid
siRNA | EZT-HFDP-1 | The Muscarinic Acetylcholine Receptor in Dermal Papilla Cells Regulates Hair Growth | bioRxiv | 2024 |
| Human Cardiac Fibroblasts cells | in vitro | plasmid | EZT-EVDY-1 | Novel and Efficient Plasmid Transfection Protocols for Functional Analysis of Genetic Elements in Human Cardiac Fibroblasts | bioRxiv | 2024 |
| U2OS cells | in vitro | plasmid | EZT-EVDY-1 | Cell surface ribonucleoproteins cluster with heparan sulfate to regulate growth factor signaling | bioRxiv | 2024 |
HEK293T cells
Melanoma cells | in vitro and in vivo | plasmid | EZT-LOXI-1 | Constitutive expression of IκBζ promotes tumor growth and immunotherapy resistance in melanoma | bioRxiv | 2024 |
| Ampho-Pack 293 cells | in vitro | plasmid | EZT-EVDY-1 | Spatial confinement induces reciprocating migration of epidermal keratinocytes and forms triphasic epithelia | bioRxiv | 2024 |
| COS-7 cells | in vitro | plasmid | EZT-EVDY-1 | Actin cytoskeletal remodeling requires the interaction between Solo and LARG in response to substrate stiffness | bioRxiv | 2025 |
| 293T cells | in vitro | plasmid | EZT-EVDY-1 | Structure and assembly of Borna disease virus 1 nucleoprotein–RNA complexes | bioRxiv | 2025 |
MDA-MB-231 cells
MDA-MB-436 cells | in vitro | plasmid | EZT-MDAM-1 | Wnt signaling promotes inflammation and EMT-associated gene expression in mesenchymal TNBC | bioRxiv | 2025 |
Human pulmonary artery endothelial cells
Human pulmonary artery smooth muscle cells | in vivo | siRNA | EZT-VIVO-1
EZT-HAOE-1 | Targeting NEDD9-SH3 with a Covalent Peptide Controls Endothelial Phenotype | bioRxiv | 2025 |
| L6-GLUT4-myc myoblast cells | in vivo and ex vivo | siRNA | EZT-L600-1 | STX4 is indispensable for mitochondrial homeostasis in skeletal muscle | bioRxiv | 2025 |
| Neuro-2a cells | | plasmid | EZT-EVDY-1 | The lipid phosphatase-like protein PLPPR1 increases cell adhesion by modulating RhoA/Rac1 activity | bioRxiv | 2018 |
| HEK 293T cells | in vitro | plasmid | EZT-EVDY-1 | It takes two vanilloid ligand bindings per channel to transduce painful capsaicin stimuli | bioRxiv | 2019 |
| HEK 293T cells | in vitro | plasmid | EZT-EVDY-1 | Birth of protein-coding exons by ancient domestication of LINE-1 retrotransposon | Genome Res | 2025 |
| RBL-2H3 cells | in vitro | plasmid | EZT-RBL2-1 | MRGPRX2-Mediated Mast Cell Degranulation by Monomethyl Methacrylate: Unveiling a Pathway in Bone Cement Implantation Syndrome | Clinical Expimental Pharmacology Physiology | 2025 |
B16-F1 cells
WM266.4 cells
HeLa cells
HEK293 cells | in vivo | siRNA | EZT-EVDY-1 | SETDB1 regulates microtubule dynamics | Cell Proliferation | 2022 |
| HeLa cells | in vitro | plasmid | EZT-EVDY-1 | Identification of BAG2 and Cathepsin D as Plasma Biomarkers for Parkinson’s Disease | Clinical and Translational Science | 2021 |
| Neuro-2a cells | in vitro | plasmid | EZT-EVDY-1 | The lipid phosphatase-like protein PLPPR1 associates with RhoGDI1 to modulate RhoA activation in response to axon growth inhibitory molecules | Journal of Neurochemistry | 2021 |
| HEK293 cells | in vitro | plasmid | EZT-EVDY-1 | Tight junction formation by a claudin mutant lacking the COOH-terminal PDZ domain-binding motif | Annals of the New York Academy of Sciences | 2022 |
| SKOV-3 cells | in vitro and in vivo | plasmid | EZT-SKOV-1 | Production of novel peptide-targeting antibodies for anti-Müllerian hormone receptor 2 and induction of cytotoxicity in ovarian cancer cells | Scandanavian Journal of Immunology | 2025 |
| WPMY-1 cells | in vitro | plasmid | EZT-PRSC-1 | ADP Ribosylation Factor 6 Promotes Contraction and Proliferation, Suppresses Apoptosis and Is Specifically Inhibited by NAV2729 in Prostate Stromal Cells | Molecular Pharmacology | 2021 |
| HeLa cells | in vitro | plasmid | EZT-EVDY-1 | Imaging single CaMKII holoenzymes at work by high-speed atomic force microscopy | Science Advances | 2023 |
| No access | No public access | No public access | No public access | Enhancing FcγR-mediated antibody effector function during persistent viral infection | Science Immunology | 2018 |
hTERT-RPE1 cells
HEK293T cells | in vitro | plasmid | EZT-EVDY-1 | Hereditary spastic paraplegia SPG8 mutations impair CAV1-dependent, integrin-mediated cell adhesion | Science Signaling | 2020 |
| C8-D30 cells | in vitro | plasmid | EZT-CRPR-1 | A Role for Basigin in Toxoplasma gondii Infection | Infection and Immunity | 2022 |
| 4T1 cells | in vitro | plasmid | EZT-4T10-1 | Overcoming resistance to αPD-1 of MMR-deficient tumors with high tumor-induced neutrophils levels by combination of αCTLA-4 and αPD-1 blockers | Journal for ImmunoTherapy of Cancer | 2022 |
| INS 832/13 cells | in vitro | plasmid | EZT-EVDY-1 | Zinc-chelating BET bromodomain inhibitors equally target islet endocrine cell types | American Journal of Physiology-Regulatory, Integrative and Comparative Physiology | 2024 |
| U251 cells | in vitro | plasmid | EZT-U251-1 | Cauliflower Mosaic Virus TAV, a Plant Virus Protein That Functions like Ribonuclease H1 and is Cytotoxic to Glioma Cells | BioMed Research International | 2020 |
| OVCAR3 cells | in vitro | siRNA
plasmid | EZT-OVC3-1 | Dimethyl Fumarate Controls the NRF2/DJ-1 Axis in Cancer Cells: Therapeutic Applications | Molecular Cancer Therapeutics | 2017 |
MDA-MB-453 cells
MDA-MB-468 cells | in vitro | plasmid | EZT-EVDY-1 | AIbZIP/CREB3L4 Promotes Cell Proliferation via the SKP2-p27 Axis in Luminal Androgen Receptor Subtype Triple-Negative Breast Cancer | Mol Cancer Res | 2024 |
| HL-60 cells | in vitro | plasmid | EZT-HL60-1 | Endogenous Retroviral Elements Generate Pathologic Neutrophils in Pulmonary Arterial Hypertension | American Journal of Respiratory and Critical Care Medicine | 2022 |
| NIH3T3-L1 cells | in vitro | plasmid | EZT-EVDY-1 | Cyclin-Dependent Kinase Inhibitor 2b Mediates Excitotoxicity-Induced Death of Retinal Ganglion Cells | Investigative Ophthalmology & Visual Science | 2019 |
EL4 (Th0, polarized Th1) cells
Th17 cells | in vitro | plasmid | EZT-EL40-1 | Blimp-1 molds the epigenetic architecture of IL-21–mediated autoimmune diseases through an autoregulatory circuit | JCI Insight | 2022 |
| Human fibroblast cells | in vitro | plasmid | EZT-EVDY-1 | Spastic paraplegia proteins spastizin and spatacsin mediate autophagic lysosome reformation | Journal of Clinical Investigation | 2014 |
| Neuro 2a cells | in vitro | plasmid | EZT-NEUR-1 | Activation of cyclin-dependent kinase 5 broadens action potentials in human sensory neurons | Molecular Pain | 2023 |
| UO-31 cells | in vitro | plasmid | EZT-UO31-1 | Camptothecin bioprocessing from Aspergillus terreus, an endophyte of Catharanthus roseus: antiproliferative activity, topoisomerase inhibition and cell cycle analysis | Microbial Cell Factories | 2024 |
| 293T cells | in vitro | plasmid | EZT-EVDY-1 | An ancient retroviral RNA element hidden in mammalian genomes and its involvement in co-opted retroviral gene regulation | Retrovirology | 2021 |
| U-2 OS cells | in vivo and ex vivo | plasmid | EZT-EVDY-1 | Liver X receptor-agonist treatment rescues degeneration in a Drosophila model of hereditary spastic paraplegia | Acta Neuropathologica Communications | 2022 |
| PC12 cells | in vitro | plasmid | EZT-PC12-1 | PLRP2 selectively localizes synaptic membrane proteins via acyl-chain remodeling of phospholipids | Journal of Lipid Research | 2020 |
| L6 cells | in vitro | plasmid | EZT-L600-1 | Digenic Variants in the FGF21 Signaling Pathway Associated with Severe Insulin Resistance and Pseudoacromegaly | Journal of the Endocrine Society | 2020 |
| CRFK cells | in vitro | miRNA | EZT-EVDY-1 | Identification of Feline Foamy Virus-derived MicroRNAs | Microbes and Environments | 2021 |
| SF268 cells | in vitro | plasmid | EZT-S268-1 | YAP1 Exerts Its Transcriptional Control via TEAD-Mediated Activation of Enhancers | PLOS Genetics | 2015 |
| Ishikawa endometrial cancer cells | in vivo | plasmid | EZT-OVC8-1 | High Glucose-Mediated STAT3 Activation in Endometrial Cancer Is Inhibited by Metformin: Therapeutic Implications for Endometrial Cancer | PLOS ONE | 2017 |
| Human Cardiac Fibroblasts cells | in vitro | plasmid | EZT-EVDY-1 | Novel and effective plasmid transfection protocols for functional analysis of genetic elements in human cardiac fibroblasts | PLOS ONE | 2024 |
A459 cells
SH-SY-5Y cells | in vitro | plasmid | EZT-A549-1
EZT-SKNS-1 | Evolution of highly pathogenic H5N1 influenza A virus in the central nervous system of ferrets | PLOS Pathogens | 2023 |
| Lamtor1‐deficient THP‐1 cells | in vitro and in vivo | plasmid | EZT-EVDY-1 | The lysosomal Ragulator complex activates NLRP3 inflammasome in vivo via HDAC6 | EMBO Journal | 2023 |
| WT cells | in vitro | plasmid | EZT-EVDY-1 | Secretion of mitochondrial DNA via exosomes promotes inflammation in Behçet's syndrome | EMBO Journal | 2023 |
| MEF cells | in vitro | plasmid | EZT-MEFS-1 | PERK signaling promotes mitochondrial elongation by remodeling membrane phosphatidic acid | EMBO Journal | 2023 |
| HL‐60 cells | in vitro | plasmid | EZT-HL60-1 | Nuclear envelope rupture and NET formation is driven by PKCα‐mediated lamin B disassembly | EMBO Reports | 2020 |
OVCAR3 (human serous ovarian carcinoma) cells
3T3 (mouse fibroblast) cells
ARPE-19 (human retinal pigment epithelium) cells
SW480 (human colon carcinoma) cells
Caco-2 (human colon carcinoma) cells
Mia Paca-2 (human pancreatic carcinoma) cells | in vitro | plasmid | EZT-OVC3-1 | Dimethyl fumarate is highly cytotoxic in KRAS mutated cancer cells but spares non-tumorigenic cells | Oncotarget | 2018 |
HEK293 cells
MCF7 cells | in vitro | plasmid | EZT-EVDY-1 | A human mitochondrial isoform of TRPV1 regulates intracellular Ca2+ simultaneously with mitochondrial thermolysis | Preprint - Not published yet | 2024 |
| Lenti-X 293T cells | in vitro and in vivo | plasmid | EZT-EVDY-1 | Cryo-EM of PMEL Amyloids Reveals Pathogenic Mechanism of Pigment Dispersion Syndrome. | Preprint - Not published yet | 2024 |
| A549 cells | in vitro | plasmid | EZT-EVDY-1 | MEIS3 is repressed in A549 lung epithelial cells by deoxynivalenol and the repression contributes to the deleterious effect | The Journal of Toxicological Sciences | 2016 |
| OVCA433 cells | in vitro | plasmid | EZT-EVDY-1 | The Biological Role of the Long Non-coding RNA LINK-A in Ovarian Carcinoma | Anticancer Research | 2020 |
| OCCM-30 cells | | siRNA | EZT-OCCM-1 | Cementogenesis is inhibited under a mechanical static compressive force via Piezo1 | The Angle Orthodontist | 2017 |
| Lamtor1‐deficient THP‐1 cells | in vitro | plasmid | EZT-EVDY-1 | The Ragulator complex and lysosomal calcium release are crucial for cell migration | Life Science Alliance | 2025 |
| L6-GLUT4-myc myoblast cells | in vitro | plasmid | EZT-L600-1 | Changes in Skeletal Muscle PAK1 Levels Regulate Tissue Crosstalk to Impact Whole Body Glucose Homeostasis | Frontiers in Endocrinology | 2022 |
| INS 832/13 cells | in vitro | plasmid | EZT-EVDY-1 | N-terminal BET bromodomain inhibitors disrupt a BRD4-p65 interaction and reduce inducible nitric oxide synthase transcription in pancreatic β-cells | Frontiers in Endocrinology | 2022 |
| HEK 293T cells | in vitro | plasmid | EZT-EVDY-1 | Two Vanilloid Ligand Bindings Per Channel Are Required to Transduce Capsaicin-Activating Stimuli | Frontiers in Molecular Neuroscience | 2020 |
| WPMY-1 cells | in vivo | siRNA | EZT-PRSC-1 | Inhibition of growth and contraction in human prostate stromal cells by silencing of NUAK1 and -2, and by the presumed NUAK inhibitors HTH01-015 and WZ4003 | Frontiers in Pharmacology | 2023 |
| Mewo cells | in vitro and in vivo | plasmid | EZT-LOXI-1 | Nuclear Glycoprotein A Repetitions Predominant (GARP) Is a Common Trait of Glioblastoma Stem-like Cells and Correlates with Poor Survival in Glioblastoma Patients | Cancers | 2023 |
| HeLa cells | in vitro | plasmid | EZT-EVDY-1 | Identification of Cathepsin D as a Plasma Biomarker for Alzheimer’s Disease | Cells | 2021 |
| HeLa cells | in vitro | plasmid | EZT-EVDY-1 | Identification of Cathepsin D as a Plasma Biomarker for Alzheimer’s Disease | Cells | 2021 |
| BmN cells | in vitro | plasmid | EZT-EVDY-1 | Leptin Is an Important Endocrine Player That Directly Activates Gonadotropic Cells in Teleost Fish, Chub Mackerel | Cells | 2021 |
| hPAEC cells | in vitro | plasmid | EZT-HUVE-1 | Caspase-6 Is a Non-Apoptotic Effector of Shear-Induced Morphological Adaptation in Pulmonary Artery Endothelial Cells In Vitro | Cells | 2025 |
| MET cells | in vitro | plasmid | EZT-EVDY-1 | Metastatic Melanoma Cells Evade Immune Detection by Silencing STAT1 | International Journal of Molecular Sciences | 2015 |
| OVCAR-8 cells | in vitro | plasmid | EZT-EVDY-1 | The Biological and Clinical Role of the Long Non-Coding RNA LOC642852 in Ovarian Carcinoma | International Journal of Molecular Sciences | 2020 |
OVCAR3 cells
OVCAR8 OC cells | in vitro | plasmid | EZT-EVDY-1 | Exosome Secretion and Epithelial-Mesenchymal Transition in Ovarian Cancer Are Regulated by Phospholipase D | International Journal of Molecular Sciences | 2022 |
| L6-GLUT4-myc myoblast cells | in vitro | plasmid | EZT-L600-1 | A Novel Role for DOC2B in Ameliorating Palmitate-Induced Glucose Uptake Dysfunction in Skeletal Muscle Cells via a Mechanism Involving β-AR Agonism and Cofilin | International Journal of Molecular Sciences | 2023 |
| 4T1-LUC cells | in vitro | shRNA
plasmid | EZT-4T10-1 | Suppression of tumor-derived Semaphorin 7A and genetic ablation of host-derived Semaphorin 7A impairs tumor progression in a murine model of advanced breast carcinoma | International Journal of Oncology | 2017 |
| KMS-11 cells | in vitro | plasmid | EZT-RPMI-1 | Unrevealed roles of extracellular enolase‑1 (ENO1) in promoting glycolysis and pro‑cancer activities in multiple myeloma via hypoxia‑inducible factor 1α | Oncology Reports | 2023 |
| HepG2-NAPRT cells | in vitro | siRNA | EZT-EVDY-1 | Effects of NAD+ Synthesis Levels on Sirtuin 1 Deacetylase Activity in Mammalian Cells | Shimane Journal of Medical Science | 2021 |
| WPMY-1 cells | in vivo | siRNA | EZT-PRSC-1 | Inhibition of prostate smooth muscle contraction and prostate stromal cell growth by the WNK inhibitor WNK463 and WNK silencing | Dissertation | 2022 |
| HEK293 cells | in vitro | plasmid | EZT-2930-1 | Charakterisierung und Funktion von TRPV2 Ionenkanälen in kortikalen Mikrogliazellen der Maus | Dissertation | 2021 |
| RAW 264.7 cells | in vitro | plasmid | EZT-RAW2-1 | Burkholderia sp. modulation of host immune response genes and pathways:: potential insights into host-pathogen interactions | Dissertation | 2017 |
| MET cells | in vitro | plasmid | EZT-EVDY-1 | Elucidation of Mechanisms Underlying Metastatic Melanoma Immune Escape via Suppression of Major Histocompatibility Complex (MHC) II through Dysregulation of the JAK/STAT Pathway | Dissertation | 2015 |
| 1.1B4 Human Pancreatic Beta cells | in vitro | plasmid | EZT-EVDY-1 | An Investigation of Coxsackie and Adenovirus Receptor in the Human Pancreatic Beta Cells | Dissertation | 2018 |
| HEK293T cells | in vitro and in vivo | plasmid | EZT-EVDY-1 | Bromodomain Binding to Metabolically-Derived Histone Lactylation and the Development of Targeted Inhibitors | Dissertation | 2025 |
| HEK293T cells | in vitro | plasmid | EZT-2930-1 | Calcium-Abhängigkeit von TRPV6-Varianten | Dissertation | 2023 |
| Mouse 4T1 cells | in vitro | plasmid | EZT-4T10-1 | Characterizing Resistance Mechanisms to Immune Checkpoint Blockades in Mismatch Repair-Deficient Tumors | Dissertation | 2021 |
| HEK293T cells | in vitro | plasmid | EZT-OVC5-1 | CRISPRi Screening in Cancer Spheroids to Investigate Factors in Genome Stability | Dissertation | 2024 |
| CD34 cells | in vivo | siRNA | EZT-RPMI-1 | Das Adaptorprotein SLy2 beim Multiplen Myelom | Dissertation | 2020 |
| 1.1B4 cells | in vitro | plasmid | EZT-OMNI-1 | Depletion of the Phosphatase Inhibitor, PPP1R1A, May Contribute to Beta-Cell Loss in Type 1 Diabetes | Dissertation | 2020 |
| HeLa cells | in vitro | plasmid | EZT-EVDY-1 | Discovery of a Novel Conformation of Human Fis1 Important for Ligand Binding and Activity | Dissertation | 2019 |
| WPMY-1 cells | in vitro | siRNA | EZT-PRSC-1 | Effects of ADP ribosylation factor 6 (ARF6) inhibition by NAV2729 or RNA interference in human prostate stromal cells | Dissertation | 2022 |
| Neuro-2a cells | in vitro | plasmid | EZT-EVDY-1 | Elucidating the Role of Plasticity-Related Gene Type 3 Protein in the Central Nervous System | Dissertation | 2018 |
| HeLa cells | in vitro | plasmid | EZT-HELA-1 | Etablierung eines Zellkulturmodells, um molekulare und zelluläre Effekte der Sec61α1R236C Mutation, die mit polyzystischer Lebererkrankung assoziiert ist, zu untersuchen | Dissertation | 2021 |
| SKOV-3 cells | in vitro and in vivo | siRNA | EZT-SKOV-1 | Folate Receptor Alpha Targeted Delivery and Characterization of Polyethyleneimine-Graft-Polycaprolactone-Blockpoly(Ethylene Glycol) Containing Sirna Micelleplexes | Dissertation | 2017 |
MDCK cells
HeLa cells | in vitro | plasmid | EZT-MDCK-1 | Intra- and Inter-Molecular Signaling in a Cardiac Connexin: Role of Cytoplasmic Domain Dimerization and Phosphorylation | Preprint - Not published yet | 2018 |
| Raji cells | in vitro | plasmid | EZT-RAJI-1 | Investigating the Role of Metastasis Suppressor 1 (MTSS1/Mim) in Cancer Biology | Dissertation | 2020 |
| U251 MG cells | in vitro | plasmid | EZT-U251-1 | Investigation of the role of US28 subcellular location in the upregulation of oncomodulatory genes in the context of glioblastoma | Dissertation | 2022 |
Human pulmonary arterial smooth muscle cells
Human pulmonary arterial endothelial cells | in vitro and in vivo | plasmid
siRNA | EZT-HAOS-1 | Loss of SMAD3 promotes vascular remodeling in pulmonary arterial hypertension via MRTF disinhibition | American Journal of Respiratory and Critical Care Medicine | 2018 |
| ARPE-19 cells | in vitro | plasmid | EZT-ARPE-1 | Molecular Regulatory Mechanism of Human Myosin-7a | Dissertation | 2024 |
| MEF cells | in vitro | plasmid | EZT-MEFS-1 | Protective eIF2α Signaling Promotes Adaptive Mitochondrial Remodeling During ER Stress | Dissertation | 2023 |
| T84 colon epithelial cells | in vivo | siRNA | EZT-T840-1 | Regulation and role of NADPH oxidase 1 in intestinal inflammation | Dissertation | 2021 |
| U251T cells | in vitro | siRNA | EZT-U251-1 | Restoring the Sphingolipid Balance in Glioblastoma | Dissertation | 2022 |
Chick Embryonic Fibroblasts
AAVpro® 293T cells
LMH cells | in vitro | plasmid | EZT-EVDY-1 | The chicken homolog of KIAA0319L functions as a receptor of avian adeno-associated virus (A3V) | Dissertation | 2021 |
| ARPE-19 cells | in vitro | plasmid | EZT-ARPE-1 | The role of CLN3 in the lysosomal-autophagosomal system | Dissertation | 2021 |
| Jurkat T-ALL cells | in vitro | plasmid | EZT-MOLT-1 | Transcriptional regulation and genome structure | Dissertation | 2018 |
HeLa cells
HEK293T cells | in vitro | plasmid | EZT-EVDY-1 | Unraveling Quality Control Pathways: The Role and Function of Parkin-Independent Mitophagy | Dissertation | 2021 |
U-2 OS cells
NIH/3T3 Tet-on cells
U-2 OS Tet-on cells
HT1080 cells | in vitro | plasmid | EZT-EVDY-1 | がん抑制因子 p27kip1 の新規な機能制御機構の解析 | Dissertation | 2021 |
| 293LTV cells | in vitro | plasmid | EZT-EVDY-1 | マスト細胞における分泌顆粒の不均質性と顆粒膜タンパク質VAMPsによる分泌機構の解析 | Dissertation | 2024 |
| MC3T3-E1 cells | in vitro | plasmid | EZT-EVDY-1 | 生物発光イメージングを用いた骨芽細胞株におけるオステオプロテゲリン分泌と RANKL によるその抑制の可視化 | Dissertation | 2024 |
