Avalanche® - The Icon of The Most Powerful Transfection Reagents

Transfection Has Never Been So Easy With Avalanche® Transfection Reagents for Cancer Cells, Primary Cells, And Other Difficult-To-Transfect Cells

View Our Products
About Us

The Transfection & Gene Delivery Experts

For the past decade, EZ Biosystems™ has dedicated itself exclusively to pioneering research, development, and manufacturing of next-generation transfection reagents. Leveraging our expertise in combinatorial chemistry, molecular biology, and cell biology, we have honed our focus on advancing transfection technology. Guided by our vision and fueled by our passion, we take pride in our position as leaders at the forefront of next-generation transfection reagent development and production. 

Featured Products

Avalanche®-Cell Type/Cell Line-specific Transffection Reagents

Perform maximum transfection efficiency for more than 180 different primary cells and cell lines

Broad Specturm Avalanche® Transfection Reagents

Exceptional transfection efficiency in the broadest range of cell types including cell lines of stem cell origin, suspension cells, and primary cells

For Biotherapeutic Protein Production

Produce the highest expression levels and transfection rates with lowest cytotoxicity in bio-production applications

Avalanche®-in vivo Transfection Reagent

For maximum delivery of DNA, shRNA, siRNA, or oligonucleotides into different organs in the body

Testimonials

What scientists are saying about Avalanche® Transfection Reagents

“Ease Of Use”

“I must say I like this system (Avalanche®), especially its ease of use and the fact that I do not need to change the media anytime after transfection.”

E Udho, Ph.D

NIH/NINDS

Higher Efficiency Than Nucleofection

LA-N-2 neuroblastoma, Ptracer-SV40 (GFP)
Avalanche®: 35% at optimal ratio (1.5 ul/2.5 ul DNA in a six well plate); Nucleofection: 31% 

C Kaneski, Ph.D

NIH/NINDS

Human Lymphocyte High Efficiency
Transfection

“Thanks again for bringing to our lab an efficient transfection reagent that worked on our difficult to transfect BJAB cell line. Results showed Avalanche® reagent to be 10X more efficient than lipofectamine and DharmaFect. We finally have the conditions to work with this cell line by using the Avalanche® Transfection Reagent”

A Fernandez, Ph.D.

NIH

Huge Differences

Tet—On Inducible NSC34 Cells, shRNA rescue by transfecting RNAi Resistant cDNA cloned into an expression vector. EGFP control plasmid,  Avalanche® efficiency 50—60%, Lipofectamine 2000/Less Than 10%, Lipofectamine 3000/Less Than 10%

C Peter, Assistant Professor

Icahn School of Medicine at Mount Sinai

“It Worked Like A Charm.”

Mouse cementoblast OCCm-30 cells. Control plasmid, YFP-N1 plasmid
Avalanche®: 80-90%; Lipofectsamine 2000: 5-10%,
“There was slight toxicity, but it worked like a charm.”

N Bhattacharyya, Ph.D.

NIH

Great On Primary Neuron Transfection

” I tested Avalanche® on primary cortical neurons and it worked much better than any other transfection reagents I’ve ever tried.”

A Caputo, PhD

David Geffen School of Medicine at UCLA

“The Readings Were So High That Most
Wells Had Overflow Readings”

“I got huge transfection efficiency (on using Avalanche®)! I am using HEKs for BRET ( like FRET but with Renilla as the donor molecule) assays and I am reading Renilla substrate and GFP excitation using a Biotek plate reader. The readings were so high that most wells had overflow readings. I was doing the same assay with Fugene transfected HEK cells an none of the wells were even close to overflow. This means that not just by looking at the microscope but even by a more precise reading at the plate reader your reagent is much superior. So now I have to scale down the amount of plasmids I transfect in HEKs because reagent is just too good!”

E Pinceti, PhD

Loyola University Chicago

Publication database and Testimonials with Avalanche® transfection reagents
Citations
Shopping Cart
Scroll to Top